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norskBlar i forfatter "Isaksen, Trond"
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Acute infection as a trigger for incident venous thromboembolism: Results from a population- based case- crossover study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-21)Background:<br> A bidirectional relation exists between acute infection and immobilization, and both are triggers for venous thromboembolism (VTE). To what extent the association between infection and VTE‐risk is explained by immobilization is unknown. <br>Aims:<br> To investigate the impact of hospitalization with acute infection on the VTE‐risk in patients with and without concomitant ... -
C-reactive protein and risk of venous thromboembolism: Results from a population-based case-crossover study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-19)Long-term, low-grade inflammation does not seem to be a risk factor for venous thromboembolism. The impact of acute inflammation, regardless of cause, on risk of venous thromboembolism is scarcely studied. We aimed to investigate the impact of acute inflammation, assessed by C-reactive protein, on short-term risk of venous thromboembolism. We conducted a case-crossover study of patients with venous ... -
Cardiorespiratory fitness and future risk of venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-25)<i>Background</i> - Cardiorespiratory fitness (CRF) is a strong predictor of future arterial cardiovascular disease and premature mortality. However, there are limited data on the association between CRF and the risk of incident venous thromboembolism (VTE).<p><p> <i>Objectives</i> - To investigate whether estimated CRF (eCRF) was associated with the risk of incident VTE in a cohort recruited ... -
Dietary intake of marine n-3 polyunsaturated fatty acids and future risk of venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-13)<p><i>Background</i>: Studies on the association between long‐chained n‐3 polyunsaturated fatty acids (n‐3 PUFAs) and risk of venous thromboembolism (VTE) are conflicting, potentially due to challenges related to assessment of n‐3 PUFA intake and changes in diet during follow‐up.</p> <p><i>Objectives</i>: To investigate whether dietary intake of marine n‐3 PUFAs was associated with risk of incident ... -
Dietary intake of marine polyunsaturated fatty acids and incidence, recurrence and mortality related to venous thromboembolism
(Doctoral thesis; Doktorgradsavhandling, 2020-11-27)Venøs tromboembolisme (VTE) er en fellesbetegnelse på dyp venetrombose (DVT) og lungeemboli (LE). VTE er en vanlig og alvorlig karsykdom hvor forekomsten har vært svakt økende de siste årene. Marine omega-3 fettsyrer (n-3 PUFAs) har flere gunstige effekter på hemostasemekanismen. Målet med denne doktorgradsavhandlingen var å undersøke sammenhengen mellom inntak av marine n-3 PUFAs i kosten og risikoen ... -
Dietary Intake of Marine Polyunsaturated n-3 Fatty Acids and Risk of Recurrent Venous Thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-28)<i>Background</i> - Limited knowledge exists on the association between intake of long-chained n-3 polyunsaturated fatty acids (n-3 PUFAs) and risk of recurrence and all-cause mortality in patients with venous thromboembolism (VTE).<p><p> <i>Objectives</i> - This article investigates whether intake of marine n-3 PUFAs was associated with risk of recurrence and mortality in patients with incident ... -
Myocardial infarction as a transient risk factor for incident venous thromboembolism: Results from a population-based case-crossover study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-16)Patients with myocardial infarction (MI) are at increased short-term risk of venous thromboembolism (VTE). The mechanisms behind this association are unclear. We aimed to investigate the impact of acute MI as a transient risk factor for incident VTE while taking other concomitant VTE risk factors into account. We conducted a case–crossover study of VTE patients (<i>n</i> = 707) recruited from the ... -
Physical activity and risk of recurrence and mortality after incident venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-15)<i>Background</i> - Limited data exist on the relationship between physical activity and major complications after incident venous thromboembolism (VTE).<p> <p><i>Objectives</i> - To investigate whether physical activity was associated with risk of recurrence and mortality in patients with VTE recruited from the general population.<p> <p><i>Methods</i> - Patients with incident VTE (n = 786) ... -
Repeated assessments of physical activity and risk of incident venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-06)<p><i>Background</i>: Whether physical activity influences the risk of incident venous thromboembolism (VTE) remains controversial, potentially because of methodological challenges, such as regression dilution bias.</p> <p><i>Objectives</i>: To investigate whether physical activity was associated with VTE risk, and explore the role of body mass index (BMI) as a mediator in a population‐based ... -
A retrospective comparison of ultrasound-assisted catheter-directed thrombolysis and catheter-directed thrombolysis alone for treatment of proximal deep vein thrombosis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016)Background: Recent studies have suggested that catheterdirected thrombolysis (CDT) reduces development of postthrombotic syndrome (PTS). Ultrasound-assisted CDT (USCDT) might enhance the efficiency of thrombolysis. We aimed to compare USCDT with CDT on efficacy, safety, development of PTS, and quality of life after longterm follow-up. <p>Methods: We describe a retrospective case series of 94 ... -
The Role of Stroke as a Trigger for Incident Venous Thromboembolism: Results from a Population-based Case-Crossover Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-22)Stroke is associated with a short-term increased risk of subsequent venous thromboembolism (VTE). It is unclear to what extent this association is mediated by strokerelated complications that are potential triggers for VTE, such as immobilization and infection. We aimed to investigate the role of acute stroke as a trigger for incident VTE while taking other concomitant VTE triggers into account. ... -
Time trends in incidence rates of venous thromboembolism in a large cohort recruited from the general population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-17)Changes in the incidence of venous thromboembolism (VTE) during the last two decades have not been extensively studied. Therefore, we studied time trends in the incidence rates (IRs) of deep vein thrombosis (DVT) and pulmonary embolism (PE) in a cohort of 26,855 subjects, aged 25–97 years, enrolled in the Tromsø study in 1994/1995. The subject were followed-up throughout 2012, and all symptomatic, ...
